The death threats against the local pharmacist Arturo Manno do not surprise any of his friends, as he is known as Casanova in the city. However, they don't really take them seriously until Manno, together with his friend Dr. Antonio Roscio, is murdered during the hunt in the early morning. Suspicion falls on the father and two brothers of a minor with whom Manno is said to have had an affair. But Professor Laurana, who had previously seen one of the ransom notes, does not believe in the guilt of the illiterate people from a run-down part of town, since the letters of the text were cut out of L'Osservatore Romano - a Christian newspaper that has few subscribers in the area. He asks his lawyer friend Rosello to take care of the arrested and begins his own investigations, motivated in part by his secret love for the widow of one of the murdered - Luisa Roscio. His trail leads him to Palermo...
"A ciascuno al suo" was the first film based on a novel by Leonardo Sciascia and is set in Sicily, Sciascia's homeland. In 1976, another collaboration between Elio Petri and Leonardo Sciascia followed in "Todo modo". Together with the film adaptations of other of his novels, "The Day of the Owl" by Damiano Damiani in 1968, the book of which was written before "Two Coffins on Order", and "Power and its Price" by Francesco Rosi in 1976, a complex picture of the political situation in Italy in the 60s and 70s emerged.